国际眼科杂志2017，Vol.17Issue(3)：451-453,3.DOI:10.3980/j.issn.1672-5123.2017.3.15
自噬与糖尿病视网膜病变研究进展
Research progress of autophagy and diabetic retinopathy
摘要
Abstract
·Diabetic retinopathy ( DR) is one of the most serious complicationsand leading causes of blindness for diabetic patients. In recent years, the incidence of DR shows a trend of rising year by year, which is a serious threat to the patients' physical and mental health. Autophagy is a very important physiological process that the cellular contents are processed by the primary lysosomes when the body is under the environment of substance and energy metabolism disorder. Autophagy belongs to one kind of the body's important defense mechanisms. According to the related clinical research data, autophagy can delay the occurrence and development of the chronic complications of diabetes to some extent, such as DR, peripheral neuropathy and diabetic nephropathy. There is a close relationship between autophagy and various relative factors of DR, such as oxidative stress and hypoxia. Therefore, the pathogenesis and treatment measures of DR have become critical research topics in clinical practice.关键词
自噬/糖尿病视网膜病变/综述Key words
autophagy/diabetic retinopathy/review引用本文复制引用
杜军辉,李蓉,马乐..自噬与糖尿病视网膜病变研究进展[J].国际眼科杂志,2017,17(3):451-453,3.基金项目
国家自然科学基金项目(No.81500726) （No.81500726）
西安市卫生局科技基金(No.2013020)@@@@National Natural Science Foundation of China ( No.81500726) （No.2013020）
Science Foundation of Xi’an Bureau of Public Health (No.2013020) （No.2013020）
