日用化学工业2017，Vol.47Issue(1)：46-51,6.DOI:10.13218/j.cnki.csdc.2017.01.010
黑素合成相关MITF基因及其表达研究概况
Situation of research work with respect to melanogenesis-associated MITF gene and its expression
摘要
Abstract
Microphthalmia-associated transcription factor (MITF)is the most important transcription factor in the melanogenesis process. MITF gene and its regulation of transcription level were presented. MITF protein and its action on melanocyte and regulation of melanogenesis,mainly via regulation of tyrosinase (TYR)gene family to control the survival and differentiation of melonocyte as well as conduction of the melanogenesis,its transportation and distribution were summarized. The application situation and prospect of MITF on cosmetics and medicine development were discussed.关键词
美白/黑素合成/小眼畸形相关转录因子/转录/调控Key words
whitening/melanogenesis/MITF/transcription/regulation分类
化学化工引用本文复制引用
杨鹏欣,刘蕾,马来记,何聪芬..黑素合成相关MITF基因及其表达研究概况[J].日用化学工业,2017,47(1):46-51,6.基金项目
北京工商大学国家两科基金资助项目 （）
