实验动物与比较医学2017，Vol.37Issue(1)：59-63,5.DOI:10.3969/j.issn.1674-5817.2016.06.013
外固定架制作兔股骨延迟愈合模型
Establishment of Femoral Delayed Healing Model with External Fixation in Rabbit
摘要
Abstract
Objective To establish a model of rabbit femoral delayed healing with the external fixation.Methods Seventy and two New Zealand white rabbits were randomly divided into three groups,including the control group,the experimental group A and experimental group B.Make osteotomies of all the animals' left femur,is in the middle,and make the micro adjustable external fixator as the fixtures.10mm cortical bone has been removed of the experimental group A and group B while removing the inner and outer periosteum and bone marrow.Keep the experimental group A 1mm gap to the fracture site.The experimental group B has been using bone wax plugging the fracture site,while maintained contact with the fracture fragments.The control group cut off the cortical bone and then fixed with the external fixator,without removing the periosteum and bone marrow.Observe the healing of osteotomy by gross observation,radiographic and histological observation postoperatively.Results The healing time of the experimental group A and group B are 12 weeks,while the control group are four weeks.Conclusion The rabbit femur fracture delayed union model has X-ray and pathological features of delayed healing,indicating that the model is reasonable and reliable关键词
模型/动物/外固定器/新西兰白兔/股骨/骨折/不愈合Key words
Models/External fixator/New Zealand White Rabbits/Femur/Fractures/Delayed healing分类
生物科学引用本文复制引用
孔庆柱,杨佳宁,王贺龙,赵胜军,孔素红,赵佳林,金宇..外固定架制作兔股骨延迟愈合模型[J].实验动物与比较医学,2017,37(1):59-63,5.基金项目
承德市科技支撑计划项目(201422036) （201422036）
