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βTCP/PLLA复合材料的制备与降解性能

马凤仓 陈赛 耿芳 刘新宽 李伟

有色金属材料与工程2016,Vol.37Issue(5):197-201,5.
有色金属材料与工程2016,Vol.37Issue(5):197-201,5.DOI:10.13258/j.cnki.nmme.2016.05.002

βTCP/PLLA复合材料的制备与降解性能

Preparation and Degradation Property of β-TCP/PLLA Composites

马凤仓 1陈赛 2耿芳 3刘新宽 1李伟1

作者信息

  • 1. 上海理工大学 材料科学与工程学院, 上海 200093
  • 2. 上海理工大学 机械工程学院, 上海 200093
  • 3. 微创骨科有限责任公司, 上海 201318
  • 折叠

摘要

Abstract

PLLA composites with various β-tricalcium phasphate(β-TCP) mass fractions were prepared by solution blended method.Pure PLLA and various composites degraded in the simulated body fluids for 3 months.Then,bending strength,tensile strength and bending modulus of the PLLA and composites were tested by universal material testing machine.Fracture of the composites was observed by SEM.The results indicate that small amount of β-TCP can increases bending strength and tensile strength of the composites.As the increase in β-TCP addition in the composites,the bending strength and tensile strength of the composite decrease,but the bending modulus of composites increases.The bending strength of the composites with different β-TCP mass fractions decreases after degradation,but the decreasing rate of the bending strength is varying with time.The bending strength of all composites decreases rapidly in the first six weeks,and the decreasing rate slows down in next six to twelve weeks,decreasing rate of bending strength of PLLA is larger than that of β-TCP/PLLA composites.Bending strength of composites is 17.8-32.4 MPa after twelve weeks degradation,and it is higher than cancellous bone whose bending strength is(11.5±2.1)MPa.The composites meet the strength requirement of the fixation for cancellous bone.

关键词

聚左旋乳酸/复合材料/力学性能/降解性能

Key words

poly-L-lactic acid/composites/mechanical property/degradation property

分类

医药卫生

引用本文复制引用

马凤仓,陈赛,耿芳,刘新宽,李伟..βTCP/PLLA复合材料的制备与降解性能[J].有色金属材料与工程,2016,37(5):197-201,5.

基金项目

国家自然科学基金项目(51471110);上海市自然科学基金项目 ()

有色金属材料与工程

2096-2983

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