摘要
Abstract
Objective:To study the correlation between platelet count and liver function recovery of hepatocel-lular carcinoma after curative resection .Methods:Platelet count ,and alanine aminotransferase (ALT ) ,aspartate aminotransferase (AST) ,glutamyl peptidase (GGT) ,alkaline phosphatase (ALP) ,total bilirubin (TB) were detec-ted in 95 cases with hepatocellular carcinoma patients after curative resection .According to the difference of the platelet count ,the two groups were divided into low platelet group and normal group .The risk factors of liver func-tion and liver function failure after operation were analyzed .Results :Among 95 cases patients of hepatocellular carci-noma treated with curative liver resection after the first day ,low platelet count was 33 cases ,accounting for 34 .7%and platelets normal was 62 cases ,accounting for 65 .3% .There were no significant differences in ALT ,AST , GGT ,ALP and TB between low platelet count group and normal platelet count group (P>0 .05) .After operation 3 weeks ,ALT ,AST ,GGT ,ALP and TB were significantly degraded(P<0 .05) ,and the levels of this stage in low platelet count group were significantly lower than those in normal platelet count group (P<0 .05) .Univariate logistic regression analysis showed TB and platelet count were risk factors for hepatectomy liver failure after radical treat-ment (OR=2 .98 ,95% CI1 .12~4 .59 ,P=0 .031;OR=4 .15 ,95% CI1 .24~5 .38 ,P=0 .006) .Conclusion :Plate-let count is closely related with liver function recovery in hepatocellular carcinoma patients after curative resection , which can be as a postoperative liver failure risk indicator ,providing the basis for clinical treatment .关键词
肝肿瘤/外科学/血小板计数/肝切除术/肝功能衰竭/预防和控制/危险因素Key words
Liver neoplasms/surgery/Platelet count/Hepatectomy/Liver/prevention & control/Risk factors分类
医药卫生
