生殖医学杂志2017,Vol.26Issue(3):283-287,5.DOI:10.3969/j.issn.1004-3845.2017.03.022
胎母输血综合征诊治进展
Progress of diagnosis and treatment of fetomaternal hemorrhage syndrome
陈沂 1胡静 2高劲松2
作者信息
- 1. 北京市大兴区人民医院妇产科,北京102600
- 2. 中国医学科学院北京协和医学院北京协和医院妇产科,北京100730
- 折叠
摘要
Abstract
Fetomaternal hemorrhage syndrome (FMH) is occult occurs,without specific clinical manifestations,and difficult to make early diagnosis.It can lead to severe fetal anemia,hydrops fetalis,and even high perinatal morbidity and mortality.Quantification of fetomaternal hemorrhage can achieved via Kleihauer-Betke test and/or flow cytometry of maternal blood samples,thus to evaluate the severity of fetal blood loss noninvasively.Other techniques such as doppler ultrasound of fetal mean cerebral artery peak systolic velocity (MCV-PSV) and maternal serum AFP (ms-AFP) may aid in the diagnosis.Termination of pregnancy is the ultimate treatment of FMH.The decision-making about personalized timing is based on fetal assessment and gestional age,taking into account of the morbidity of prematurity,the risk of in utero therapy,and the uncertain clinical course of expectant management.Experienced intrauterine transfusion is critical in the prolongation of pregnancy in case of severe anemia to avoid extreme preterm birth.关键词
胎母输血综合征/诊断/治疗Key words
Fetomaternal hemorrhage syndrome/Diagnosis/Treatment引用本文复制引用
陈沂,胡静,高劲松..胎母输血综合征诊治进展[J].生殖医学杂志,2017,26(3):283-287,5.