天津中医药2017,Vol.34Issue(3):212-216,5.DOI:10.11656/j.issn.1672-1519.2017.03.18
甘草化学成分植物雌激素活性研究进展
Advances study of phytoestrogen from licorice
摘要
Abstract
Licorice, isolated from Fabaceae Glycyrrhiza, is an essential traditional Chinese medicine. Flavonoids and triterpenoids play main roles among 400 compounds, identified from Licorice. Due to phytoestrogenic activity, flavonoids are broadly used for clinical treat-ment, including breast cancer, neuropathic, cardiovascular and other various diseases via PI3K/Akt and MAPK pathways. This review fo-cuses on the molecular mechanisms and clinical applications of phytoestrogen from licorice, based on database of China National Knowl-edge Infrastructure(CNKI) and PubMed, which sheds lights on the clinical treatment and drug discovery of phytoestrogen from licorice.关键词
甘草/黄酮类/植物雌激素/雌激素受体Key words
licorice/flavonoids/phytoestrogen/estrogen receptor分类
医药卫生引用本文复制引用
韩静,邵瑞,王跃飞,王彧..甘草化学成分植物雌激素活性研究进展[J].天津中医药,2017,34(3):212-216,5.基金项目
国家自然科学基金青年科学基金资助项目(81202877) (81202877)
天津市应用基础与前沿技术研究计划(14JCYB-JC42900). (14JCYB-JC42900)