中国组织工程研究2017，Vol.21Issue(7)：1041-1045,5.DOI:10.3969/j.issn.2095-4344.2017.07.011
水对骨组织生物摩擦学损伤多尺度的有限元分析
Multilevel finite element analysis on the biological tribology damage of water on bone tissue
摘要
Abstract
BACKGROUND:Many studies reported the relationship of the mechanical properties and water content about bone tissue, which is one of organizations containing the lowest water content on human body. Researches on effect of water on biological tribology behavior of bone tissue have been rarely reported and are the experimental study generally. OBJECTIVE:To explore the influence and the damage mechanism of water on biological tribology behavior of bone tissue, by comparing multiscale numerical model established with the experiment. METHODS:Dehydration of the bone tissue was studied by nanoindentation test and both reciprocating sliding and impact wear tests. A multi-scale finite element model was constructed under a flat-on-ball configuration. RESULTS AND CONCLUSION:The viscoelasticity and the tribological properties of bone tissue significantly decreased as well as the different wear mechanisms under applied loading after drying. The analytical results indicated that there were high stress condition, which incurred the micro-crack initiation and the appearance of peeling and wear, around the Haversian canal, circumferential lamellas and the interstitial tissues. Meso-scale:dehydration weakened the function of absorption and interruption of stress, which facilitated crack extension in pore. Micro-scale:the high stress gradient of structure of canaliculi and lacunae is an important cause of tissue damage.关键词
骨科植入物/数字化骨科/骨组织/水/有限元分析/损伤/国家自然科学基金分类
医药卫生引用本文复制引用
何泽栋,赵婧,陈亮宇,李科,翁杰..水对骨组织生物摩擦学损伤多尺度的有限元分析[J].中国组织工程研究,2017,21(7):1041-1045,5.基金项目
国家自然科学基金资助项目(51205327) （51205327）
高等学校博士学科点专项科研基金资助项目(20120184120019) （20120184120019）
中央高校基本科研业务费专项资金资助项目(2682014SWJTU11CX020) the National Natural Science Foundation of China, No. 51205327 （2682014SWJTU11CX020）
the Special Research Foundation of Doctoral Course in Colleges and Universities, No. 20120184120019 （）
the Special Fund for Basic Scientific Research of Central University, No. 2682014SWJTU11CX020 （）
