心理科学进展2017，Vol.25Issue(3)：452-462,11.DOI:10.3724/SP.J.1042.2017.00452
肥胖成因的解释——基于食物奖赏研究的视角
The cause of obesity: An explanation from food reward perspective
摘要
Abstract
Food is a natural rewarding stimulus,which promotes human to seek for it because of their instinctive desire and need for reward."Wanting","liking" and "learning & reinforcement" are three main components of food reward,and each of them is represented in its corresponding neural pathway.Food reward regulates food intake behavior and body weight.The association between food reward and obesity has predominantly been explained by three main theoretic models,namely the incentive sensitization theory of addiction,the reward-surfeit theory of obesity and the reward deficit theory of obesity.In human studies,the association between food reward and obesity has usually been studied by using a cross-sectional design,perspective design or longitudinal within-subjects design,in which either food pictures or palatable liquid foods (such as milkshake) were used as the experimental stimuli to obtain brain responses to food cues or actual foods,respectively.In addition,human brain response to both food cues and actual foods is regulated by the human genome.The role of single nucleotide polymorphisms (SNPs) in dopamine D2 receptor gene TaqIA rs 1800497 and the FTO gene rs9939609 is discussed in the current review.关键词
肥胖/食物奖赏/fMRI/TaqIA/FTOKey words
obesity/food reward/fMRI/TaqIA/FTO分类
社会科学引用本文复制引用
韩艳,舍英,高笑..肥胖成因的解释——基于食物奖赏研究的视角[J].心理科学进展,2017,25(3):452-462,11.基金项目
国家自然科学基金项目(31100758)和中央高校基本科研业务费重点项目SWU1409116. （31100758）
