新医学2017，Vol.48Issue(2)：124-127,4.DOI:10.3969/j.issn.0253-9802.2017.02.012
监测降钙素原及血小板的变化在胆总管结石治疗中的应用价值
Application value of monitoring the changes of procalcitonin and platelet in the treatment of common bile duct stones
江庆斌 1陈白丽 1李东松 1郑春毅 1武魁1
作者信息
- 1. 521000 潮州，潮州市人民医院普通外科
- 折叠
摘要
Abstract
Objective To investigate the application value of the changes of procalcitonin and plate-let in the treatment of common bile duct stones.Methods Clinical data of 80 patients diagnosed with common bile duct stones were retrospectively analyzed.According to the diagnostic criteria of systemic inflammatory re-sponse syndrome (SIRS),all patients were divided into the SIRS (n =40)and non-SIRS groups (n =40). The values of procalcitonin,white blood cell,C-reactive protein and platelet were detected at 1 ,3,5 and 7 d after admission.The effect of common bile duct stones complicated with SIRS upon these parameters was evalu-ated.The optimal inflammatory parameters of SIRS were identified.The score of APACHE Ⅱ was calculated. The relationship between the changes of procalcitonin and platelet and APACHE Ⅱ score was investigated.Re-sults SIRS was a factor affecting the changes of procalcitonin and platelet (both P <0.01 ).The area under the ROC curve of procalcitonin and platelet was 0.82 and 0.87,which had a relatively high accuracy in the di-agnosis of SIRS.The changes of procalcitonin and platelet were significantly correlated with APACHE Ⅱ score (r =0.89 and 0.88,both P <0.01 ).Conclusions SIRS is a pivotal factor affecting procalcitonin and plate-let.Procalcitonin is an appropriate index for monitoring common bile duct stones complicated with acute cholan-gitis.Monitoring the changes of procalcitonin and platelet plays a vital role in the early diagnosis of common bile duct stones,assessment of the severity of diseases and offering guidance to clinical treatment.关键词
胆总管结石/降钙素原/血小板Key words
Common bile duct stone/Procalcitonin/Platelet引用本文复制引用
江庆斌,陈白丽,李东松,郑春毅,武魁..监测降钙素原及血小板的变化在胆总管结石治疗中的应用价值[J].新医学,2017,48(2):124-127,4.
