新医学2017，Vol.48Issue(2)：132-136,5.DOI:10.3969/j.issn.0253-9802.2017.02.014
右小腿腺泡状软组织肉瘤一例
Alveolar soft part sarcoma in the right lower extremity:a case report
赵小晓 1黄征 1谢永辉 1章宏峰1
作者信息
- 1. 430000 武汉，华中科技大学同济医学院附属武汉中心医院病理科
- 折叠
摘要
Abstract
Alveolar soft part sarcoma (ASPS)is a rare highly malignant soft tissue neoplasm.In this article,we reported one 1 7-year old male patient diagnosed with ASPS in the deep soft tissues of his right lower extremity.Microscopically,the neoplasm was manifested with solid texture,loss of alveolar structure and sepa-rated by fibrovascular septa.A large quantity of blood sinus was observed and tumor thrombosis was identified within the blood vessels.Needle-like crystals were detected in the cytoplasm of tumor cells.Immunohistochemi-cal staining revealed that the tumor cells were positive for TFE3 nucleus,partially positive for SMA,partially positive for F8,dispersely positive for Vimentin,positive for Periodic acid-Schiff staining and negative for alter-native parameters.After enlarged tumor resection,the tumor-free survival of the patient achieved 1 4 months. This case prompts that combined application of clinical,histological and morphological characteristics and im-munohistochemical examinations contributes to accurate diagnosis of ASPS.Abundant blood sinus and perivas-cular or cytoplasmic eosin-stained transparent tumors should be excluded for the differential diagnosis of ASPS. TFE3 is a specific biomarker.关键词
腺泡状软组织肉瘤/病理诊断/鉴别诊断/治疗/预后Key words
Alveolar soft part sarcoma/Pathological diagnosis/Differential diagnosis/Treatment/Prognosis引用本文复制引用
赵小晓,黄征,谢永辉,章宏峰..右小腿腺泡状软组织肉瘤一例[J].新医学,2017,48(2):132-136,5.
