摘要
Abstract
Objective To evaluate the clinical efficacy of endovascular interventional embolization in the treatment of different middle cerebral artery(MCA)aneurysms. Methods A total of 192 patients diag-nosed with MCA aneurysms undergoing endovascular interventional embolization were recruited in this clinical trial. Preoperative Hunt-Hess classification,postoperative Glasgow outcome scale (GOS),incidence of postop-erative complications,quality of life at postoperative 6 months [The Short Form Health Survey (SF-36 )]and recurrence of aneurysms within postoperative 1 year were obtained. Surgical efficacy was statistically compared among different patients according to single onset,preoperative rupture of aortic aneurysms,tumor size,com-plete initial embolization and incidence of postoperative complication. Results The percent age of 192 patients with 0-V grade of Hunt-Hess classification was 14. 1%,14. 6%,41 . 1%,28. 1%,1 . 6%and 0. 5%,respec-tively. The quantity of 192 patients who obtained GOS score of 1-5 was 1 ,19,28,86 and 58,respectively. The mean SF-36 score at postoperative 6 months was 65. 5 ±23. 2. The GOS (U=9. 941 ,P=0. 019)and SF-36 scores (t=2. 023,P=0. 045)in patients with complete initial embolization were significantly higher com-pared with those in their counterparts with incomplete initial embolization. The SF-36 score in patients with postoperative complications was significantly lower than that in those without postoperative complications (t=-2. 237,P=0. 026). The incidence of transient cerebral ischemia in patients with multiple aortic aneurysms was significantly higher compared with that in those with single MCA aneurysm (χ2 =8. 495,P=0. 004). The recurrence rate within postoperative 1 year in patients without preoperative rupture of MCA aneurysms was sig-nificantly higher than that in those with preoperative rupture of MCA aneurysms (χ2 =8. 921 ,P=0. 003 ). Conclusions Endovascular interventional embolization is an efficacious treatment of MCA aneurysms. Howev-er,surgical efficacy significantly varies according to complete initial embolization,postoperative complications,different quantities of MCA aneurysms and preoperative rupture of MCA aneurysms.关键词
大脑中动脉/动脉瘤/介入治疗Key words
Middle cerebral artery/Aortic aneurysm/Interventional therapy
