烟草科技2017，Vol.50Issue(1)：58-66,9.
分散液液微萃取-GC-MS/MS法测定卷烟主流烟气粒相物中的农药残留
Determination of pesticide residues in particulate matter of mainstream cigarette smoke by dispersive liquid-liquid microextraction and gas chromatography-tandem mass spectrometry
陈晓水 1杨洋 1汤晓东 1蒋佳磊 1赵路灿 1张宸 1朱书秀 1陆明华1
作者信息
- 1. 浙江中烟工业有限责任公司技术中心，杭州市西湖区转塘镇科海路118号 310024
- 折叠
摘要
Abstract
In order to quantify the pesticide residues in particulate matter of mainstream cigarette smoke, a procedure using acetonitrile-based extraction combined with dispersive liquid-liquid microextraction (DLLME) and gas chromatography-tandem mass spectrometry (GC-MS/MS) detection was developed for determining the residues of 63 pesticides. The effects of extraction solvent type and volume, extraction time were investigated and optimized. The total particulate matter of mainstream cigarette smoke collected by a Cambridge filter pad was extracted with acetonitrile under oscillation, the extract was further disposed by DLLME, the obtained tetrachloromethane extract was analyzed by GC-MS/MS and quantified by internal standard method. The results showed that good linearity was observed for all 63 analytes with the correlation coefficients ranged from 0.994 9 to 1.000 0. The limits of quantification were no more than 10 ng/cig, and the average recoveries were 75.6%-127.5% with RSD from 0.5% to 19.0% at three different spiked levels. This method is simple, accurate, sensitive and suitable for the determination of 63 pesticide residues in particulate matter of mainstream cigarette smoke.关键词
卷烟/主流烟气/粒相物/分散液液微萃取(DLLME)/气相色谱-串联质谱(GC-MS/MS)/农药残留Key words
Cigarette/Mainstream cigarette smoke/Particulate matter/Dispersive liquid-liquid microextraction (DLLME)/Gas chromatography-tandem mass spectrometry(GC-MS/MS)/Pesticide residue分类
轻工纺织引用本文复制引用
陈晓水,杨洋,汤晓东,蒋佳磊,赵路灿,张宸,朱书秀,陆明华..分散液液微萃取-GC-MS/MS法测定卷烟主流烟气粒相物中的农药残留[J].烟草科技,2017,50(1):58-66,9.
