中国医疗设备2017，Vol.32Issue(2)：68-70,3.DOI:10.3969/j.issn.1674-1633.2017.02.018
超声在研究肾癌彩色血流平均密度与微血管密度相关性中的应用
Application of Color Doppler Ultrasound in Analyzing Correlation Between Mean Color Vessel Density and Micro Vessel Density in Renal Cell Carcinoma
崔涛 1葛明珠 2赵燕辉 1张延辉 1徐涛 1刘春雷1
作者信息
- 1. 青岛市中心医院泌尿外科,山东青岛266042
- 2. 青岛市肿瘤医院腹部超声科,山东青岛266042
- 折叠
摘要
Abstract
Objective To explore the correlation between preoperative mean color vessel density (MCVD) tested by ultrasound and postoperative histopathological grade in pathology,micro vessel density (MVD) in renal cell carcinoma.Methods 69 cases of renal cell carcinoma patients confirmed via surgical pathology were examined with ultrasound preoperatively,and their MCVD were calculated according to the results of color power angiography.After operation all the slices of tumor tissue specimens were stained with routine hematoxylin-eosin (HE) staining method and immunohistochemistry staining method respectively.The tumor tissue specimens stained by HE were graded in histopothology.lmmunohlstochemistry staining was done with instant-type mouse anti-human CD34 monoclonal antibody and used to calculate MVDs.Then MCVD,MVD and histopathological grades were analyzed statistically.Results As MCVD value was higher in kidney lesion,the detected MVD value increased more,both showing positive correlation (r=0.998,P＜0.05) in this study.Histopathology was graded Ⅰ-Ⅲ after operation.MVD and MCVD in different histopathological grades were different statistically (P＜0.05).Conclusion The preoperative MCVD value generated by ultrasound showed good correlation with the postoperative histopathological grade as well as MVD,and ultrasonic detection had the characteristics of no wound,repeatability,which could be used as a reliable method of preoperatively evaluating angiogenesis in renal cell carcinoma.MCVD had important instructive clinical significance to renal cell carcinoma for early diagnosis,treatment and evaluating prognosis,etc.关键词
超声/彩色血流平均密度/肾肿瘤/微血管密度/病理组织学Key words
ultrasonography/mean color vessel density/kidney neoplasms/micro vessel density/histopathology分类
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崔涛,葛明珠,赵燕辉,张延辉,徐涛,刘春雷..超声在研究肾癌彩色血流平均密度与微血管密度相关性中的应用[J].中国医疗设备,2017,32(2):68-70,3.
