中国医疗设备2017，Vol.32Issue(2)：91-95,5.DOI:10.3969/j.issn.1674-1633.2017.02.025
质谱仪在乳腺癌生物标记物研究中的应用
Application of Mass Spectrometer in the Study of Breast Cancer Biomarkers
唐武芳 1吴超超 2范海伟 2高强2
作者信息
- 1. 江苏盐城市城南医院设备处,江苏盐城224001
- 2. 浙江佰辰医疗科技有限公司研发部,浙江杭州310030
- 折叠
摘要
Abstract
Breast cancer is a kind of common malignant tumor threatening women's health.At present,histopathological factor is the main clinical basis for breast cancer forecast and treatment.Discovery and confirmation of biomarkers based on clinical proteomics study has gradually become the mainstream of breast cancer research,which greatly enhances clinical understanding of molecular mechanism of breast cancer,and promotes the clinical diagnosis and prognosis of breast cancer.This article mainly reriewed the application progress of mass spectrometry in the study of breast cancer biomarkers.Firstly,it introduced basic concept of proteomics based on mass spectrometry,then detailed the latest research progress on mass spectrometry techniques and related application in breast cancer biomarker research,furthermore it also listed some potential breast cancer biomarkers with mass spectrometry as well as their application prospect.Finally,the limitations and future development trend of mass spectrometry in breast cancer biomarker study were also discussed.关键词
质谱分析/乳腺癌/生物标记物/蛋白质组学/同位素标记Key words
mass spectrometry/breast cancer/biomarker/proteomics/isotope labeling引用本文复制引用
唐武芳,吴超超,范海伟,高强..质谱仪在乳腺癌生物标记物研究中的应用[J].中国医疗设备,2017,32(2):91-95,5.
