摘要
Abstract
Objective To comparatively analyze the range and clinical prognosis of cervical lymph node dissection in resection surgical of differentiated thyroid carcinoma if color Doppler ultrasound was used or not before operation. Methods Total 80 patients with differentiated thyroid carcinoma who were diagnosed successively from March 2012 to March 2014, were selected and divided into control group (n=36) and observation group (n=44) according to the order of admission. The study had been approved by ethics committee of our hospital, as well as respecting patient and relative's right of informed consent. All patients were performed total or subtotal thyroidectomy, and control group underwent non or simple cervical lymph node dissection based on the operators' experience, while observation group underwent cervical lymph node dissection at the maximum range in view of examination of high frequency color Doppler ultrasound before operation. Results With follow-up one year, the recurrence rate of tumor in observation group was significantly lower than that of control group, and the survival rate was significantly higher, the differences were statistically significant (P<0.05). However, the difference had no statistical significance in incidence of operative complications in the two groups (P>0.05). For comparing the preoperative diagnosis of lymph node metastasis by high frequency color Doppler ultrasound and intraoperative confirmed detection, the sensitivity was 97.4%, specificity was 33.3%, positive predictive value was 90.2% and negative predictive value was 66.7%. Conclusion Preoperative diagnosis of differentiated thyroid carcinoma by high frequency color Doppler ultrasound could be combined to cervical lymph node dissection at the dissection range after surgery of resecting thyroid tissue so as to increase accuracy, decrease recurrence and make a good effect, which had a great reference value.关键词
分化型甲状腺癌/淋巴结清扫/高频彩超/甲状腺切除术/肿瘤复发Key words
differentiated thyroid carcinoma/cervical lymph node dissection/high frequency color Doppler ultrasound/thyroidectomy/tumor recurrence分类
医药卫生
