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唑来膦酸注射液对原发性骨质疏松患者体温的影响

张春燕 任晓蕾 张海英 张斌 冯婉玉

医药导报2017,Vol.36Issue(2):213-215,3.
医药导报2017,Vol.36Issue(2):213-215,3.DOI:10.3870/j.issn.1004-0781.2017.02.024

唑来膦酸注射液对原发性骨质疏松患者体温的影响

Influence of Zoledronic Acid Injection on Body Temperature of Patients with Primary Osteoporosis

张春燕 1任晓蕾 1张海英 1张斌 1冯婉玉1

作者信息

  • 1. 北京大学人民医院药剂科,北京100044
  • 折叠

摘要

Abstract

Objective To investigate the influence of zoledronic acid injection on body temperature of patients with primary osteoporosis.Methods A total of 142 patients with primary osteoporosis who received intravenous zoledronic acid treatment in Peking university people's hospital during 2013-2014 were enrolled in this study.The body temperature before and after intravenous zoledronic acid treatment were recorded and analyzed with SPSS 17.0 software.Results The patients'body temperature at different time points after intravenous zoledronic acid treatment was significantly different (P =0.000).Prophylactic use of NSAIDs could significantly reduce patients' body temperature at the second day after intravenous zoledronic acid.Conclusion NSAIDs can be given orally on the same day of intravenous injection of zoledronic acid,and continued for three days.

关键词

唑来膦酸注射液/体温/预防用药

Key words

Zoledronic acid injection/Body temperature/Prophylactic use

分类

医药卫生

引用本文复制引用

张春燕,任晓蕾,张海英,张斌,冯婉玉..唑来膦酸注射液对原发性骨质疏松患者体温的影响[J].医药导报,2017,36(2):213-215,3.

医药导报

OA北大核心CSTPCD

1004-0781

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