应用化学2017，Vol.34Issue(3)：324-329,6.DOI:10.11944/j.issn.1000-0518.2017.03.160243
甘油作溶剂、微波促进苯并噁唑类化合物的合成
Microwave-Assisted Synthesis of Benzoxazoles in Glycerol
摘要
Abstract
Benzoxazole derivatives are well known for their applications in medicinal,industrial and synthetic organic chemistry.Numerous effects has been focused on developing efficient methods for the synthesis of it.The benzoxazole derivatives was synthesised by condensation of 2-aminophenol and benzaldehyde in presence of glycerol under focused microwave-irradiation conditions.Reaction conditions:2-aminothiophenol (1.0 mmol),benzaldehyde(1.0 mmol),glycerol (2 mL),irradiating under focused microwave for several minutes at 20 W and 110 ℃.The corresponding products was obtained in 80％ to 91％ yield.The present method has the advantages of mild conditions,green solvent,simple operation,easily available reaction substrates,and excellent product yields,which make it a useful and important supplement to the existing methods.关键词
苯并噁唑/甘油/邻氨基苯酚/芳香醛Key words
benzoxazole/glycerol/aminophenol/aromatic aldehydes分类
化学化工引用本文复制引用
雷蛟,罗丽,付维维,周文俊..甘油作溶剂、微波促进苯并噁唑类化合物的合成[J].应用化学,2017,34(3):324-329,6.基金项目
四川省教育厅成果转化培育项目(15CZ0026)和内江师范学院博士科研启动费(2012B05)资助 （15CZ0026）
Supported by the Sichuan Province Education Office Fostering Projects(No.15Z0026),the Startup Foundation of Ph.D.Scientific Research of Neijiang Normal University(No.2012B05) （No.15Z0026）
