针刺研究2017，Vol.42Issue(1)：85-89,5.DOI:10.13702/j.1000-0607.2017.01.016
针刺镇痛的新思路——针灸参与疼痛多维度调节的可行性
New Trains of Thoughts About Acupuncture Analgesia——Acupuncture Analgesia May Involve Multi-dimensional Regulation of Pain
摘要
Abstract
With the development of pain study,researchers gradually recognized that pain is composed of three main dimensions,namely "sensory-discriminative" "affective-motivational" and "cognitive-evaluative" which influence each other and are also independent from each other.Pain study has shifted away from focusing on the single mode of nociception to the multi-dimensional mode of sensory-affection-cognition.It is held early in traditional Chinese medicine that "when there is a stoppage,there is a pain" and a worsening disease may induce depression,which has already shown a multi-dimensional recognition about pain.Acupuncture therapy has been considered to be an effective adjuvant approach for relieving pain.In the present paper,the authors introduced applicability of acupuncture analgesia by modulating the abovementioned multi-dimensions of pain from the following 4 aspects:1) multi-dimensions of pain and related brain regions;2) recognitions of traditional Chinese medicine about pain;3) development of researches on acupuncture analgesia,including a) balancing activities of endogenous analgesic and algogenic substances,and triggering intracellular mitogen-activated protein kinase (MAPK) signaling to reduce algesia,b) improving psychological symptoms of patients with depression,anxiety,insomnia,etc.,c) modulating functional activities of some common brain regions (as hippocampus,anterior cingutate,frontal lobe of cerebral cortex,etc.) sharing both pain information and learning-memory processing.Hence,the authors hold that if the clinical study and application and experimental researches conducted on the underlying mechanisms of acupuncture analgesia extend towards the multi-dimensions of pain,a series of new concepts or thoughts will be brought out,thereby possibly opening a bright applicable prospect for acupuncture analgesia.关键词
针刺镇痛/疼痛/多维度/感觉/情绪/认知Key words
Acupuncture analgesia/Pain/Multi-dimensions/Sensation/Affection/Cognition分类
医药卫生引用本文复制引用
方剑乔,邵晓梅..针刺镇痛的新思路——针灸参与疼痛多维度调节的可行性[J].针刺研究,2017,42(1):85-89,5.基金项目
国家自然科学基金(No.81473772、81574056) （No.81473772、81574056）
浙江省医药卫生重大科技计划(No.WKJ-2 J-1419) （No.WKJ-2 J-1419）
浙江省自然科学基金(No.LY 15 H 270009) （No.LY 15 H 270009）
