诊断学理论与实践2017，Vol.16Issue(1)：104-108,5.DOI:10.16150/j.1671-2870.2017.01.020
正弦图确定迭代重建在低剂量胸部CT筛查中的应用
Application of sinogram-affirmed iterative reconstruction technique in low-dose lung CT screening
摘要
Abstract
Objective:To compare the performance difference on image quality between sinogram-affirmed iterative reconstruction (SAFIRE) and filtered back projection (FBP)in low-dose lung CT screening. Methods:A total of 304 pa-tients receiving annual low-dose lung CT screening were examined by a dual-source CT system at 120 kV with reference tube current of 40 mA·s. Six image serials were reconstructed, including one dataset of FBP and five datasets of SAFIRE with different reconstruction strengths from 1 to 5 (S1 to S5). Image noise and subjective scores of image noise were recorded. Images artifacts and overall image quality were also assessed by two radiologists. Results: The mean weight and the body mass index of patients were (66.3 ±12.8) kg and 23.4 ±3.2, respectively. The mean dose-length product was (95.2±30.6) mGy·cm, and the effective dose was (1.6±0.5) mSv. The observation agreement for image noise grade, artifact grade and the overall image quality was in good consistency (r=0.785, 0.595 and 0.512). Among the overall six datasets, both the scores of measured mean objective image noise and the subjective image noise of FBP were the highest, and the image noise decreased with the increasing of SAFIRE reconstruction strength. The datasets of S3 obtained were the highest quality scores for image. Conclusions:Compared with FBP, SAFIRE reconstruction may significantly improve image quality in low-dose lung CT screening and SAFIRE with reconstruction strength 3 is a pertinent choice for low-dose lung CT.关键词
肺/计算机体层摄影/图像重建/放射剂量Key words
Lung/Computed tomography/Image reconstruction/Radiation dose分类
医药卫生引用本文复制引用
吴梦雄,曹琪琪,杨文洁,严福华,颜凌..正弦图确定迭代重建在低剂量胸部CT筛查中的应用[J].诊断学理论与实践,2017,16(1):104-108,5.基金项目
上海市科学技术委员会医学重点项目子课题(13411950105) （13411950105）
