中国病理生理杂志2017，Vol.33Issue(3)：562-566,5.DOI:10.3969/j.issn.1000-4718.2017.03.031
Wip1相关研究进展
Progress in the role of Wip1
摘要
Abstract
Wildtype p53-induced phosphatase 1 (Wip1) is a serine/threonine protein phosphatase of 605 ami-no acids, which is expressed at high levels in many organs and tissues .As Wip1 is overexpressed in human tumors , analy-sis of Wip1 has focused primarily on its role in tumorigenesis .In recent years , it has also been shown that Wip 1 plays an important role in several physiological processes including adult neurogenesis , senescence , immunodeficiency and metabolic diseases.This review addresses how Wip1 participates in physiological and pathological conditions at cellular and molecular levels.关键词
Wip1/肿瘤/衰老/免疫/炎症/代谢Key words
Wip1/Tumor/Senescence/Immune/Inflammation/Metabolism分类
医药卫生引用本文复制引用
刘可美,颜红兵..Wip1相关研究进展[J].中国病理生理杂志,2017,33(3):562-566,5.基金项目
国家自然科学基金资助项目(No.81270288 （）
No.81541095) （）
