中国当代儿科杂志2017，Vol.19Issue(3)：280-285,6.DOI:10.7499/j.issn.1008-8830.2017.03.006
孤独症谱系障碍儿童表情面孔工作记忆的事件相关电位研究
Event-related potential of working memory on emotional faces in children with autism spectrum disorder
摘要
Abstract
Objective To investigate the characteristics of working memory ability on emotional faces and related event-related potential (ERP) in children with autism spectrum disorder (ASD).Methods The Chinese Facial Affective Picture System was used as test material,and the event-related potential system was used to record the electroencephalographic data when 16 ASD children aged 6-12 years (ASD group) and 14 normal children matched for age (control group) were completing the facial emotion delayed match-to-sample task.The characteristics of P3b component were analyzed for both groups.Results Compared with the control group,the ASD group had a significantly longer reaction time (1 527 ms vs 1 060 ms;P＜0.05) and a significantly lower accuracy rate (76％ vs 88％;P＜0.01) in the facial emotion delayed match-to-sample task.There was a difference in the amplitude of P3b component during the encoding stage between the two groups.In the ASD group,the P3b component on the left side electrode had a higher amplitude than that on the right side electrode (P＜0.05),while the control group had no such characteristics.Conclusions There is a difference in P3b component during the encoding stage between school-aged ASD children and normal children.In ASD children,working memory on emotional faces may depend more on the related neural pathway in the left hemisphere.关键词
孤独症谱系障碍/表情面孔/工作记忆/事件相关电位/儿童Key words
Autism spectrum disorder/Emotional face/Working memory/Event-related potential/Child引用本文复制引用
许才娟,张玲,潘宁,林琼希,叶俊,静进,金宇..孤独症谱系障碍儿童表情面孔工作记忆的事件相关电位研究[J].中国当代儿科杂志,2017,19(3):280-285,6.基金项目
国家自然科学基金(81171293). （81171293）
