中国临床药理学与治疗学2017，Vol.22Issue(2)：194-197,4.
前交叉韧带重建术后患者感染治疗方案的选择与个体化用药的思考
Role of clinical pharmacists in the anti-infective therapy after anterior cruciate ligament reconstructions: an individualized medicine perspective
于洋 1何佳珂 2熊爱珍 2丁楠2
作者信息
- 1. 上海第二军医大学附属长海医院药学部,上海200433
- 2. 南昌大学第二附属医院药学部,南昌330006,江西
- 折叠
摘要
Abstract
AIM:To explore the role of clinical pharmacists participating in the individualized antiinfective therapy after anterior cruciate ligament reconstruction.METHODS:Clinical pharmacists participated in the therapy for a patient with staphylococcus aureus infection after anterior cruciate ligament reconstruction.According to patient's condition,clinical pharmacist assisted physicians to formulate preliminary anti-infection plan.Embarking on drug sensitivity test,clinical pharmacist carried out individualized medication for patient by vancomycin serum concentration monitoring and population pharmacokinetic modeling.Close pharmaceutical care were conducted throughout the therapy.Moreover,clinical pharmacist assisted physicians to evaluate the therapeutic efficacy.RESULTS:According to vancomycin serum concentrations,clinical pharmacist suggested physician to change the anti-infection plan,and received a good therapeutic effect.CONCLUSION:Clinical pharmacists participate in the anti-infective therapy after anterior cruciate ligament reconstruction,and the designs of individualized dosing regimens contribute in the safety and effectiveness of drug use in patients with serious infection.关键词
个体化用药/抗感染/药动学模型/临床药师Key words
individualized medicine/anti-infective therapy/pharmacokinetic modeling/clinical pharmacists分类
医药卫生引用本文复制引用
于洋,何佳珂,熊爱珍,丁楠..前交叉韧带重建术后患者感染治疗方案的选择与个体化用药的思考[J].中国临床药理学与治疗学,2017,22(2):194-197,4.
