中国临床药理学与治疗学2017，Vol.22Issue(2)：210-214,5.
中枢σ-2受体对神经精神疾病影响和治疗的研究进展
Research advance of central σr-2 receptor on the pathogenesis and therapeutics of neuropsychiatric diseases
摘要
Abstract
Recent studies indicated that the central σ-2 receptor may play an important role in the pathogenesis and therapeutics of neuropsychiatric diseases.In the recent years,its neurobiological functions have attracted great attention with the emergence of available new selective σr-2 receptor ligands.Several new studies suggest that σ-2 receptor is a part of PGRMC1,shading new light on and direction for the function investigation of σ-2 receptor.Thus,in this review,the physiological functions of σ-2 receptor in the central nervous system,and the involvement of σ-2 receptor in various neuropsychiatric diseases and related treatment are discussed.关键词
σ-2受体/孕激素受体膜组分1/神经精神疾病Key words
S σ-2 receptor/PGRMC1/neuropsychiatric diseases分类
医药卫生引用本文复制引用
吴艳琴,江沛,谭亲友,徐萍,李焕德,蔡骅琳..中枢σ-2受体对神经精神疾病影响和治疗的研究进展[J].中国临床药理学与治疗学,2017,22(2):210-214,5.基金项目
国家自然科学基金青年基金项目(81401113,81602846,81101001) （81401113,81602846,81101001）
国家自然科学基金地区基金项目(81360665) （81360665）
国家教育部博士点新教师类基金项目(20130162120060) （20130162120060）
