中国临床药理学与治疗学2017,Vol.22Issue(2):222-227,6.
长链非编码RNA在结直肠癌中的作用
Role of lncRNAs in colorectal cancer
摘要
Abstract
Long non-coding RNAs (lncRNAs) are important regulative RNAs whose length are more than 200 nucleotides and cannot be translated into protein.Recent studies have shown that lncRNAs play important roles in the tumor development,invasion and metastasis,early diagnosis,prognosis,chemo-resistance and radio-resistance of colorectal cancer (CRC).CRC is a common gastrointestinal cancer with high morbidity and mortality.Currently,there are some relevant studies on the role of lncRNAs in the development,chemor-esistance and radio-resistance of CRC.Yet this paper reviews the latest international researches in this regard.关键词
结直肠癌/长链非编码RNA/肿瘤Key words
colorectal cancer/lncRNA/tumor分类
医药卫生引用本文复制引用
孙跃胜,屈强,潘江华,童晓春,陈恩德,屈健..长链非编码RNA在结直肠癌中的作用[J].中国临床药理学与治疗学,2017,22(2):222-227,6.基金项目
国家自然科学基金(81503166,81603208) (81503166,81603208)
中南大学湘雅医院青年科研基金(2014Q08) (2014Q08)