中国临床医学2017，Vol.24Issue(1)：31-36,6.DOI:10.12025/j.issn.1008-6358.2017.20161131
轻度创伤性脑损伤后磁敏感加权成像脑内微出血与外伤后抑郁发生的相关性
Relationship between microbleeds on susceptibility-weighted MRI and newly-developed depression in patients after mild traumatic brain injury
朱萍 1李跃华 2李晓兵 1魏小二 2汪璇2
作者信息
- 1. 上海市第六人民医院南院奉贤区中心医院放射科,上海 201400
- 2. 上海市第六人民医院放射科,上海 200233
- 折叠
摘要
Abstract
Objective:To explore the relationship between abnormality on susceptibility-weighted imaging (SWI)and newly-developed depression after mild traumatic brain injury.Methods:Totally 200 brain injury patients with routine CT and MRI were examined.All patients underwent MRI including conventional MR sequences and SWI.The number and volume of microbleed lesions were semi-automatically outlined and manually counted.All patients were followed up with the Structured Clinical Interview for DSM-Ⅳ Axis I Disorders (SCID-Ⅳ)within 1 year after TBI.Results:The difference in microbleed lesions on SWI was compared between the depressive and non-depressive groups.The depressive group had a higher rate of abnormality on SWI than which in the non-depressive group (P<0.001 ).Among patients that had exhibited microbleed lesions,the number and volume of lesions were greater in the depressive group than the non-depressive group (allP<0.001). These differences in numbers and volume of lesions were found only at the frontal,parietal,and temporal lobes (all P<0.001).Among patients that had exhibited microbleed lesions,the number and volume of lesions in other areas were not significantly different between the depressive and non-depressive groups.Conclusions:SWI was useful to identify the microbleed lesions after mild TBI.The distribution range and location of microbleed lesions were correlated with depression after TBI.关键词
创伤性脑损伤/抑郁/磁共振成像/磁敏感加权成像/微出血Key words
traumatic brain inj ury/depression/magnetic resonance imaging/susceptibility-weighted分类
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朱萍,李跃华,李晓兵,魏小二,汪璇..轻度创伤性脑损伤后磁敏感加权成像脑内微出血与外伤后抑郁发生的相关性[J].中国临床医学,2017,24(1):31-36,6.
