中国临床医学2017，Vol.24Issue(1)：86-88,3.DOI:10.12025/j.issn.1008-6358.2017.20170053
肺癌组织环指蛋白RNF38的表达及其临床意义
Expression of RNF38 in lung cancer and its clinical significance
摘要
Abstract
Objective:To investigate the expression of RNF38 in lung cancer,and its correlationship with clinicopathologic feature and prognosis.Methods:Tissue microarray was used to detect the level of RNF38 in 208 lung cancer patients,then its correlationship with clinicopathologic feature and prognosis was analyzed.Results:RNF38 expression was higher in lung cancer tissues compared with the corresponding adjacent normal lung tissues.High level of RNF38 was related significantly to tumor size (P= 0.0002),tumor stage (P= 0.011),lymph node metastasis (P= 0.00004)and histological type (P= 0.030 ).High level of RNF38 indicates low overall survival rate.Single factor analysis showed that RNF38 expression was related to lung cancer patients'prognosis.Conclusions:The high level of RNF38 could be a new marker in predicting the prognosis of lung cancer.关键词
RNF38/肺癌/预后Key words
RNF38/lung cancer/prognosis分类
医药卫生引用本文复制引用
李继军,金淳,熊点,蒋家好,丁建勇..肺癌组织环指蛋白RNF38的表达及其临床意义[J].中国临床医学,2017,24(1):86-88,3.基金项目
国家自然科学基金(81201834,81502502).Supported by National Natural Science Foundation of China (81201834,81502502). （81201834,81502502）
