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新西兰大白兔组织工程骨的构建及体内异位成骨效果

李海旭 石继祥 石文俊 刘孚瑛 章筛林 周强

中国临床医学2017,Vol.24Issue(1):89-92,4.
中国临床医学2017,Vol.24Issue(1):89-92,4.DOI:10.12025/j.issn.1008-6358.2017.20160775

新西兰大白兔组织工程骨的构建及体内异位成骨效果

The structure analysis of ectopic bone formed by engineered bone in the New-Zealand rabbits

李海旭 1石继祥 1石文俊 1刘孚瑛 1章筛林 1周强1

作者信息

  • 1. 上海中医药大学附属普陀医院骨科,上海 200062
  • 折叠

摘要

Abstract

Objective:To study the structure of ectopic bone formed beside the New-Zealand rabbit femoral bone. Methods:Bone marrow stroma stem cells (BMSCs)were taken from New-Zealand rabbits to built engineered bone constructs, the constructs were embedded near the rabbit femoral bone,the ectopic bone constructs were harvested at 8th week for further examination and study.Results:At 8th week,the ectopic bone had a clear bone-like structure,together with new blood supply, green fluorescent protein could be seen in samples seeded by marked cells.Conclusions:This study showed that the ectopic bone formation could be successfulinvivo.

关键词

组织工程骨/异位成骨/结构

Key words

engineered bone constructs/ectopic bone formation/structure

分类

医药卫生

引用本文复制引用

李海旭,石继祥,石文俊,刘孚瑛,章筛林,周强..新西兰大白兔组织工程骨的构建及体内异位成骨效果[J].中国临床医学,2017,24(1):89-92,4.

基金项目

上海市卫生和计划生育委员会科研课题(20114205).Supported by Research Project of Shanghai Health and Family Planning Commission (20114205). (20114205)

中国临床医学

OACSTPCD

1008-6358

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