中国临床医学影像杂志2017，Vol.28Issue(3)：188-192,5.
探讨18F-FDG PET/CT在非小细胞肺癌放射治疗靶区勾画及临床分期中的价值
Application value of 18F-FDG PET/CT in delineation of radiotherapy target area and clinical stage in non-small cell lung cancer
赵晓晓 1阮翘 1谢新立 1常伟 1赵苏丹 1赵曦曈 1韩星敏1
作者信息
- 1. 郑州大学第一附属医院核医学科,河南郑州450052
- 折叠
摘要
Abstract
Objective:To explore the application value of 18F-FDG PET/CT in delineation of radiotherapy target area and clinical stage in non-small cell lung cancer,and to provide a basis for formulation of treatment plan.Methods:Eighty patients confirmed with non-small cell lung cancer by cytology or pathology and suitable for radiotherapy from January 2014 to November 2015 in our hospital were enrolled in this study.In which,51 cases were squamous cell carcinoma,29 cases were adenocarcinoma.Breast enhancement CT and 18F-FDG PET/CT were performed in all patients,and GTVPET/CT and GTVCT were determined,and the difference was compared statistically.Results:①GTVPET/CT ((20.74±15.57)cm3) was 24.16％ smaller than GTVCT((26.33±17.31) cm3),and the difference was statistically significant(P＜0.05).②GTVCT and GTVP,ET/CT were (27.85±15.79)cm3 and (22.35±14.06) cm3 respectively in squamous carcinoma group,GTVCT and GTVPET/CT were (25.46±18.21) cm3 and (19.83± 16.44) cm3 respectively in adenocarcinoma group,and GTVCT were bigger than GTVPET/CT in both groups,and the difference was significant statistically(P＜0.05).③18F-FDG PET/CT changed the clinical stage in 46 patients(57％) in all patients,in which 35 cases were up regulated,11 cases were down regulated.Conclusion:18F-FDG PET/CT can be helping in distinguishing tumor tissue with the surrounding atelectasis or inflammation,and in delineation of radiotherapy target area,and also in accurate clinical staging.关键词
癌,非小细胞肺/氟脱氧葡萄糖F18/正电子发射断层显像术Key words
Carcinoma, non-small-cell lung/Fluorodeoxyglucose F18/Positron-emission tomography分类
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赵晓晓,阮翘,谢新立,常伟,赵苏丹,赵曦曈,韩星敏..探讨18F-FDG PET/CT在非小细胞肺癌放射治疗靶区勾画及临床分期中的价值[J].中国临床医学影像杂志,2017,28(3):188-192,5.
