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胰腺导管内乳头状黏液肿瘤的分子病理学研究进展

王福栋 宁振 王阿曼

中国普通外科杂志2017,Vol.26Issue(3):359-366,8.
中国普通外科杂志2017,Vol.26Issue(3):359-366,8.DOI:10.3978/j.issn.1005-6947.2017.03.014

胰腺导管内乳头状黏液肿瘤的分子病理学研究进展

Progress on molecular pathology of intraductal papillary mucinous neoplasms

王福栋 1宁振 1王阿曼2

作者信息

  • 1. 大连医科大学附属第一医院肝胆外科,辽宁 大连 116011
  • 2. 大连医科大学附属第一医院肿瘤科,辽宁 大连 116011
  • 折叠

摘要

Abstract

Intraductal papillary mucinous neoplasms (IPMNs) are a rare type of pancreatic cystic tumor, with risk of transforming to pancreatic ductal adenocarcinoma and once it occurs may confer a poor prognosis. Currently, studies on IPMNs are still scarce at home and abroad. Therefore, better understanding the molecular pathological mechanism responsible for IPMNs may have great importance in diagnosis and treatment as well as improving the prognosis of IPMNs. A great amount of oncogenes, tumor suppressor and signaling molecules have been found involving the process of occurrence and development of IPMNs as well as the malignant transformation. In this paper, the authors mainly address the research progress on molecular pathology of IPMNs.

关键词

胰腺肿瘤/导管内乳头状黏液肿瘤/病理学,分子/综述文献

Key words

Pancreatic Neoplasms/Intraductal Papillary Mucinous Neoplasms/Pathology/Molecular/Review

分类

医药卫生

引用本文复制引用

王福栋,宁振,王阿曼..胰腺导管内乳头状黏液肿瘤的分子病理学研究进展[J].中国普通外科杂志,2017,26(3):359-366,8.

中国普通外科杂志

OA北大核心CSCDCSTPCD

1005-6947

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