中国全科医学2017，Vol.20Issue(7)：800-803,4.DOI:10.3969/j.issn.1007-9572.2017.07.008
老年急性胰腺炎患者的临床特点及预后研究
Clinical Features and Outcome of Acute Pancreatitis in Elderly Patients
摘要
Abstract
Objective To investigate the clinical features and outcome of acute pancreatitis (AP ) in the elderly. Methods The subjects enrolled in this study were 1382 consecutive AP patients admitted to Guangdong General Hospital from November 2005 to October 2015. By checking medical records,we obtained the clinical data of them,including gender, age,etiology distribution of AP,severity staging of AP,complications,length of stay,recurrence rate and mortality. Based on age,we divided the patients into the elderly group (aged 60 or over,n = 678)and the control group (younger than 60 years old,n = 704). Results Significant gender difference in the incidence of AP was found between the two groups (P < 0. 05). The incidence of AP due to biliary disease in the control group and elderly group was 46. 4% (327 / 704)and 76. 8% (521/ 678),respectively. Etiology distribution of AP differed remarkably between the groups (P < 0. 05),while the severity staging of AP did not (P > 0. 05). With regard to the incidence of local complications,the incidences of acute peripancreatic fluid collection,acute necrotic collection and pancreatic pseudocyst were significantly higher in the control group than in the elderly group (P < 0. 05),but the incidences of encapsulated necrosis,walled - off pancreatic necrosis,hydrothorax,gastrointestinal fistula,intra - abdominal hemorrhage,pancreatic pseudocyst bleeding,splenic/ portal vein thrombosis and necrotic colitis were not (P > 0. 05). In terms of the incidence of systemic complications,the incidences of systemic inflammatory response syndrome (SIRS),intra - abdominal hypertension (IAH)or abdominal compartment syndrome (ACS)were significantly higher in the control group than in the elderly group (P < 0. 05),but the incidences of organ failure and systemic infection were not (P >0. 05). Two groups had similar length of stay and mortality (P > 0. 05),however,the elderly group had significantly higher recurrence rate (P < 0. 05). Conclusion Biliary pancreatitis was the most common to be seen in the elderly group. Elderly and control groups had similar severity staging of AP,length of stay and mortality,but the former had higher proportion of women with AP,and recurrence rate.关键词
胰腺炎/疾病特征/预后/老年人Key words
Pancreatitis/Disease attributes/Prognosis/Aged分类
医药卫生引用本文复制引用
王蓓蓓,廖山婴,聂胜利,沙卫红,布小玲,马娟..老年急性胰腺炎患者的临床特点及预后研究[J].中国全科医学,2017,20(7):800-803,4.基金项目
国家自然科学基金资助项目(81001112) （81001112）
