中国全科医学2017，Vol.20Issue(9)：1110-1116,7.DOI:10.3969/j.issn.1007-9572.2017.09.017
宫颈癌患者同步放化疗期间症状群的调查研究
Symptom Clusters of Patients with Cervical Cancer during Concurrent Chemoradiation Therapy
摘要
Abstract
Objective To explore the symptom clusters and symptoms distribution of patients with cervical cancer during concurrent chemoradiation therapy. Methods From November 2015 to June 2016,according to the inclusion criteria, 137 patients with cervical cancers during concurrent chemoradiation therapy in radiation therapy center from 3 tertiary hospitals:the Affiliated Hospital of Xuzhou Medical University,Xuzhou Central Hospital and General Hospital of Xuzhou Coal Mining Group were selected by convenient sampling method. One - to - one interview was conducted to all the subjetcs. The questionnaire included demographic data,clinical data and the Memory Symptom Assessment Scale in Chinese version (MSAS - Ch). Results In this study,137 questionnaires were sent out and 124 valid questionnaires were collected. The effective response rate was 90. 5%. The average age of the 124 patients with cervical cancer was (51. 5 ± 8. 6). The symptoms of the top five incidence in the concurrent chemoradiation period of the patients with cervical cancer were fatigue (97. 6%,121 / 124),loss of appetite (87. 9%,109 / 124 ),dry mouth (83. 9%,104 / 124 ),skin change (81. 5%,101 / 124 ),and nausea (80. 6%,100/ 124). There was a positive correlation between the incidence of fatigue and loss of appetite,between the incidence of loss of appetite and changing of taste,between the incidence of dry mouth and diarrhea,between the incidence of skin change and abdominal distension,between the incidence of nausea and changing of taste,between the incidence of nausea and diarrhea, and between the incidence of changing of taste and diarrhea (P < 0. 05). Seven symptom clusters including gastrointestinal symptom clusters,energy deficiency symptom clusters,perimenopausal symptom clusters,self - image impaired symptom clusters,somatic - related symptom clusters,nervous system - related symptom clusters,psychological symptom clusters were got by exploratory factor analysis method. The total variance contribution rate was 56. 985%. The variance contribution rate of each symptom cluster was 9. 972%, 9. 117%, 8. 256%, 8. 214%, 7. 376%, 7. 033% and 7. 017%, respectively. The Cronbach′s α of each symptom cluster was 0. 853,0. 812,0. 798,0. 870,0. 775,0. 846,0. 913,respectively. Conclusion There are various symptom clusters in cervical cancer patients during concurrent chemoradiation therapy,so clinical nurses should actively promote symptom management,and improve the quality of life of patients during treatment.关键词
宫颈肿瘤/化放疗/症状和体征Key words
Uterine cervical neoplasms/Chemoradiotherapy/Symptoms & signs分类
医药卫生引用本文复制引用
何明喻,刘桂红,徐继承..宫颈癌患者同步放化疗期间症状群的调查研究[J].中国全科医学,2017,20(9):1110-1116,7.基金项目
江苏高校哲学社会科学研究项目(2015-SJB414) （2015-SJB414）
