中国输血杂志2017，Vol.30Issue(1)：19-21,3.DOI:10.13303/j.cjbt.issn.1004-549x.2017.01.006
江苏地区汉族人群血小板CD36抗原表达差异的研究
Study on diverse expression of platelets CD36 antigen in Han population in Jiangsu, China
摘要
Abstract
Objective To investigate CD36 expression levels in platelets in the Jiangsu Han population.Methods CD36 expression levels on platelets were analyzed by flow cytometry among 140 blood donors in Jiangsu region.Results In these 140 blood donors,CD36-deficient and CD36-expression individuals were 2.86％ (4/140) and 97.14％ (136/140),respectively.Among 136 individual with platelet CD36 expression,according to mean fluorescence intensity (MFI) value,29,93 and 14 individuals showed low,moderate and high expression levels of CD36,respectively,and their MFIs were 1 821.4±21.8;93,3 920.4±10.0 and 8 787.4±63.7 (P＜0.05),respectively.Of the 136 individuals,the MFI CD36 expressions levels were 3 678.36± 13.5 in 127 males and 5 296.0± 14.4 in 9 females,respectively.Conclusion Platelet CD36 surface expression levels are diverse in the Jiangsu Han population.关键词
CD36抗原/血小板/血小板膜糖蛋白Ⅳ/流式细胞术/江苏汉族Key words
CD36 antigen/platelets/platelet membrane glycoprotein Ⅳ/flow cytometry分类
医药卫生引用本文复制引用
庄云龙,段志敏,陈蓉,蔡莉,肖建宇,黄成垠,李岷,陈青..江苏地区汉族人群血小板CD36抗原表达差异的研究[J].中国输血杂志,2017,30(1):19-21,3.基金项目
江苏省重点研发计划社会发展项目(BE2015717),江苏省“十二五”期间“科教兴卫工程”医学重点人才(RC2011088),江苏省第十批“六大人才高峰”项目(2013-WSW-039),江苏省第四期和第五期“333高层次人才培养工程”,2010、2014年度江苏省卫生国际交流支撑计划项目资助,山东省医药卫生科技发展计划重点项目(2013WS0170) （BE2015717）
