中国输血杂志2017，Vol.30Issue(1)：45-48,4.DOI:10.13303/j.cjbt.issn.1004-549x.2017.01.014
自身免疫性溶血性贫血患者输血治疗的回顾性分析
Retrospective analysis on transfusion efficiency in patients with autoimmune hemolytic anemia
王立新 1陈春霞 1魏曾珍 1谭金哲 1吴秋月 1秦莉1
作者信息
- 1. 四川大学华西医院实验医学科,四川成都610041
- 折叠
摘要
Abstract
Objective To analyze the transfusion efficiency of autoimmune hemolytic anemia patients (AIHA) and to provide eVidence for clinical blood transfusion.Methods The serological characteristics and the incidence of adverse transfusion reactions of 72 patients with idiopathic or secondary AIHA from 2011 to 2014 were analyzed retrospectively.The efficiency and safety of RBC transfusion were evaluated based on the different kinds of infused blood components and the compatibility of blood products.Results Forty six patients were transfused 131 times without any adverse transfusion reactions.There were 89 transfusions that can be analyzed.The total efficiency rate,total partial efficiency rate and total inefficiency rate were 56.2％,37.1％ and 6.7％,respectively.According to the results from the crossmatch,the patients were divided into either compatible group or minimal mismatched group.The efficiency rate,the partial efficiency rate and the inefficiency rate in compatible group was 54.5％,41％ and 4.5％,respectively,while in the minimal mismatched group,the rates were 56.7％,35.8％ and 7.5％,respectively.There were no significant differences of transfusion efficacy (P＞0.05) in two groups.According to the different kinds of infused blood products,the patients were divided into washed RBC group and non-washed RBC group.The efficiency rate,partial efficiency rate and inefficiency rate in washed group (62.5％,31.3％ and 6.2％) were not significantly different from the non-washed group (54.8％,38.4％ and 6.8％).Conclusion Transfusion is efficient for the AIHA patients with severe anemia.Transfusion with the non-washed and washed RBC of the same ABO types is relatively safe for patients with severe anemia.Minimally mismatched blood product is comparatively safe when antibody cannot be identified in an emergency.关键词
自身免疫性溶血性贫血/输血/回顾分析Key words
autoimmune hemolytic anemia/transfusion efficiency/retrospective analysis分类
医药卫生引用本文复制引用
王立新,陈春霞,魏曾珍,谭金哲,吴秋月,秦莉..自身免疫性溶血性贫血患者输血治疗的回顾性分析[J].中国输血杂志,2017,30(1):45-48,4.
