中国实验动物学报2017，Vol.25Issue(1)：107-110,4.DOI:10.3969/j.issn.1005-4847.2017.01.020
Beagle犬卵母细胞体外成熟研究进展
Research progress of in vitro maturation of Beagle dog oocytes
摘要
Abstract
Sufficient embryos are needed for the preservation of Beagle dogs germplasm resources and the prepara-tion of gene?modified human disease animal models. Up to now, the induced ovulation technique has no effect on dogs,it is hard to obtain mature oocytes in vivo, although the scientists try a lot in many aspects, but still could not make a break?through. The in vitro maturation rate is too low to support the preservation of germplasm resources, application in gene?modified disease models and biomedical research. Aiming to provide useful information on breakthrough in dog oocytes mat?uration, this review will summarize the effect of different age and reproductive stage,different morphology and size of the oo?cytes and lipid droplet on the in vitro maturation of dog oocytes.关键词
犬/疾病模型/卵母细胞/体外成熟Key words
Beagle dogs/Disease model/Ooocytes/in vitro maturation分类
生物科学引用本文复制引用
胡敏华,周治东,倪庆纯,刘运忠..Beagle犬卵母细胞体外成熟研究进展[J].中国实验动物学报,2017,25(1):107-110,4.基金项目
广州市"珠江科技新星"项目(201610010144) （201610010144）
广州市科技基础条件平台建设项目(201605040005). （201605040005）
