中国比较医学杂志2017，Vol.27Issue(2)：29-32,4.DOI:10.3969.j.issn.1671-7856.2017.02.006
大鼠子宫角瘘管模型的建立
Establishment of a rat model of uterine horn fistula
摘要
Abstract
Objective To explore the feasibility of catheter implantation in a rat model of uterine horn fistula. Methods The catheter was placed into the uterine horns at one side in the rats, then histopathology and pregnancy function were studied. Results The endometrial thickness of the fistula side in the fistula model group (497. 68 ± 81. 64μm) was not significantly different compared with the control group (537. 90 ± 77. 29 μm) and the opposite side (503. 56 ±76.34 μm) (P>0.05). The number of embryo breeding in the fistula model group (9.67 ±1.95) was significantly decreased compared with the control group (12. 15 ± 2. 06). The number of embryo breeding of the fistula side (5. 83 ± 3. 54) was not significantly different compared with the opposite side (6. 17 ± 3. 67 ) (P>0. 05). Conclusions The effect of catheter on uterine tissue and pregnancy function is minimal, and the model of uterine horn fistula applies to the requirement of long term injection of pathogenic microorganisms or drugs.关键词
大鼠/子宫角/瘘管模型Key words
Rat/Uterine horn/Fistula model分类
医药卫生引用本文复制引用
侯金龙,袁超文,黄欢宇,王国卿..大鼠子宫角瘘管模型的建立[J].中国比较医学杂志,2017,27(2):29-32,4.基金项目
教育部中央高校基本科研业务费(N130420001). （N130420001）
