摘要
Abstract
Objective To explore the application of oropharyngeal pH-monitoring in diagnosis for children with suspected LPR-related respiratory symptoms.Methods Children suffering from airway-related problems with suspected LPR between October 2015 and February 2016 were included in this descriptive qualitative study.All subjects underwent oropharyngeal 24-hour pH-monitoring.The positive rate of RYAN index,demographic data,distribution of clinical presentation and initial diagnosis among the positive LPR patients were analyzed.Results The study included 76 subjects with the age range between 1 month and 12 years old with a mean age of 4.9 years old.All patients successfully completed 24-hour of pH recording and the positive rate of RYAN index was 39.5％(30/76),LPR in younger group was higher than that in the older group.Some LPR patients treated with omeprazole reported RYAN index negtive after 8 weeks of follow-ups.LPR-related presentation included chronic cough,wheezing,snore,hoarseness,throat clearing,choking sucking,foaming at the mouth,stridor,shortness of breath,facial cyanosis and nasal obstruction.Meanwhile,those patients were mostly diagnosed with airway diseases,such as pneumonia,sinusitis and rhinitis,laryngomalacia,pharyngitis,asthmatic bronchitis,adenoid hypertrophy,etc.Conclusion Clinical manifestations of LPR are nonspecific and may lead to misdiagnosis.Being minimally invasive and easy for operation,oropharyngeal 24-Hour pH-monitoring can be conducted for children at all ages,and may be considered as the standards for diagnosis of pediatric laryngopharyngeal reflux.关键词
24h口咽pH监测/咽喉反流/儿童/诊断Key words
24h pharyngeal pH-monitoring/laryngopharyngeal reflux/child/diagnosis分类
医药卫生
