中国实用妇科与产科杂志2017，Vol.33Issue(3)：319-323,5.DOI:10.19538/j.fk2017030120
细菌潜生体与盆腔脓肿发病相关性研究
Study on the association between pelvic abscess and the cryptic growth cell
摘要
Abstract
Objective To study the antibiotic function of inducing the E.coli to Cryptic Growth Cells(CGC)and its correlation with pelvic abscess.Methods Establish the models of pelvic inflammatory disease(PID);Use the SD female rats as research subjects;inculate the E.coli on the mesosalpinx;observe the pathological changes of reproductive system;determine the acute exacerbation.Establish PID acute exacerbation models and divide them into 4 groups:one for control and the other 3 for experiment.Use 1/2 concentration antibiotics to induce the CGC to simulate denormalized treatment.Observe the pathological change and CGC.Results In the PID models,the pathological change and time had positive correlation.Among these models,the course of PID was divided into acute and chronic stage.The acute exacerbation was defined as the range between 7th to 17th days after modeling,but there was no suppuration during that time.CGC was found from the models which were injected 1/2 concentration of cephalosporins during the acute exacerbation.At the same time,lesions appeared suppuration and serious tissue damage.Conclusion CGC can be induced by nonstandard antibiotic treatment for PID,which may induce pelvic abscess.关键词
盆腔脓肿/细菌潜生体/大肠埃希菌Key words
pelvic abscess/cryptic growth cell/E.coli分类
医药卫生引用本文复制引用
孙海珠,刘晶晶,路莉,王德莹,陈秀慧,赵吉子,邱晓红..细菌潜生体与盆腔脓肿发病相关性研究[J].中国实用妇科与产科杂志,2017,33(3):319-323,5.基金项目
黑龙江省自然科学基金(H2013106) （H2013106）
