中国实用内科杂志2017，Vol.37Issue(3)：251-254,4.DOI:10.19538/j.nk2017030116
Ⅰ型心肾综合征危险因素分析
Risk factor analysis of type Ⅰ cardiorenal syndrome
摘要
Abstract
Objective To learn about the incidence of type Ⅰ cardiorenal syndrome analyze the risk factor and assess the relationship between clinical index and degree of acute kidney injury (AKI).Methods The data were collected from 2009 to 2015 in patients with acute heart failure.The average hospitalization days and hospital mortality were compared between AKI group and non-AKI group.The independent risk factors of type Ⅰ cardiorenal syndrome were screened by logistic regression analysis.The relevances between age,hospitalization time,New York Heart Association (NYHA) classification of cardiac function,oliguria,EF,TNI,hs-CRP,BNP,CK-MB,LDH,D-D,Fg,Tp,ALB,Cr,TG,TC,LDL-c,HDL-c,HB,and the degree of kidney injury were analyzed by correlation analysis.Results In a total of 481 patients,the incidence of AKI was 37.84％.Hospitalized mortality rate AKI group was 3.83 times that of non-AKI group (x2=14.07,P＜0.01).The average hospitalization days in AKI group was significantly more than that in non-AKI group(U=22390,P＜0.01).The age,history of previous nephropathy,hypertension,oliguria,low high density lipoprotein cholesterol,fibrinogen and elevated,anemia were independent risk factor of type Ⅰ cardiorenal syndrome.The equation of regression is logitP=-6.28+0.03 × age+1.56 × history of previous nephropathy+0.18 × hypertension+1.27 × oliguria,+0.54 × low high density lipoprotein cholesterol+0.57 × fibrinogen elevated+0.69 × anemia.With the increase of NYHA classification of cardiac function,oligufia,BNP,D-D and Cr,ALB and Hb decreased,and the level of kidney injury increased.Conclusion Type Ⅰ cardiorenal syndrome is the common complication of the acute heart failure,which increases the hospitalization days and hospital mortality.We should reduce the incidence of type Ⅰ cardiorenal syndrome by controlling the relevant risk factors.关键词
Ⅰ型心肾综合征/急性心功能不全/急性肾损伤Key words
type Ⅰ cardiorenal syndrome/acute heart failure/acute kidney injury分类
医药卫生引用本文复制引用
徐天华,刘芳婕,张琢,吴雪莹,王力宁,马健飞,冯江敏,姚丽..Ⅰ型心肾综合征危险因素分析[J].中国实用内科杂志,2017,37(3):251-254,4.基金项目
国家“十二五”科技支撑计划项目子课题(2011BAI10B02) （2011BAI10B02）
沈阳市科学技术计划攻关项目(F16-206-9-04) （F16-206-9-04）
卫生公益性行业科研专项(201502010) （201502010）
