中国现代医学杂志2017，Vol.27Issue(3)：18-21,4.DOI:10.3969/j.issn.1005-8982.2017.03.004
不同提取方法的紫地榆提取物对常驻口腔细菌的研究
Effect of Geranium Strictipes extracts extracted by different methods on acid production of three strains of oral bacteria
摘要
Abstract
Objective To inquire into the effect of N-butyl alcohol and ethyl acetate extracts of Geranium Strictipes extracted by different methods on growth and acid production of Streptococcus mutans,Streptococcus sanguis and Actinomyces viscosus.Methods Firstly,minimum bacteriostatic concentration (MIC) and minimum bactericidal concentration (MBC) of N-butyl alcohol and ethyl acetate extracts of Geranium Strictipes extracted by different methods on Streptococcus mutans,Streptococcus sanguis and Actinomyces viscosus were respectively determined and then the effect of these Geranium Strictipes extracts on the acid production was determined.Results The MIC of N-butyl alcohol extract of Geranium Strictipes extracted reflux on Streptococcus mutans,Streptococcus sanguis and Actinomyces viscosus were 3.0,3.0 and 6.0 g/L respectively,while the MBC were 6.0,6.0 and 12.0 g/L respectively.The MIC of ethyl acetate extract of Geranium Strictipes extracted reflux on the three bacteria strains were all 6.0 g/L,and the MBC were all 12.0 g/L.The MIC of N-butyl alcohol extract of Geranium Strictipes extracted maceration on the three bacteria strains were all 6.0 g/L,the MBC were all 12.0 g/L.The MIC of ethyl acetate extract of Geranium Strictipes extracted maceration on the three bacteria strains were all 6.0 g/L,the MBC were all 12.0 g/L.A certain concentration of N-butyl alcohol and ethyl acetate extracts of Geranium Strictipes could inhibit acid production of the three bacteria strains,but there was no significant difference in the inhibition of acid production by different extraction methods.Conclusions N-butyl alcohol and ethyl acetate extracts of Geranium Strictipes can effectively inhibit the growth and acid production of oral bacteria,may be effective anti-caries agents.关键词
紫地榆/变形链球菌/粘性放线菌/血链球菌/产酸Key words
Geranium Strictipes/Streptococcus mutans/Streptococcus sanguis/Actinomyces viscosus/acid production分类
医药卫生引用本文复制引用
杨晓珍,蓝海..不同提取方法的紫地榆提取物对常驻口腔细菌的研究[J].中国现代医学杂志,2017,27(3):18-21,4.基金项目
国家自然科学基金(No:81260512) （No:81260512）
云南省大理学院应用开发研究基金(No:Kyyy201102) （No:Kyyy201102）
