摘要
Abstract
Objective To investigate the effect of glycated albumin (GA) on homocysteine in diabetic patients complicated with acute cerebral infarction. Methods A total of 236 acute cerebral infarction patients with diabetes were chosen and divided into group A (93 case, GA <17.0%) and group B (143 cases, GA≥17.0%). Height, weight, blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglyceride, fasting blood glucose, glycated albumin, and plasma homocysteine were detected and compared. Results The levels of glycated albumin and fasting blood glucose were significantly higher in the group B compared with the group A (P<0.05). The level of homocysteine was 14.91 (11.47, 20.24) μmol/L in the group A and 16.22 (12.40, 25.13) μmol/L in the group B, there was significant difference (P<0.05). The level of homocysteine was positively correlated with the levels of GA and fasting blood glucose, but negatively associated with the level of total cholesterol. GA elevation was an independent factor related to increased plasma homocysteine level. Conclusions The plasma level of homocysteine increases in diabetic patients with acute cerebral infarction who have high glycated albumin level.关键词
糖尿病/脑梗死/糖化白蛋白/同型半胱氨酸Key words
diabetes mellitus/cerebral infarction/glycated albumin/homocysteine分类
医药卫生
