中国药房2017，Vol.28Issue(5)：602-606,5.DOI:10.6039/j.issn.1001-0408.2017.05.07
我院肿瘤患者止吐药物使用合理性与疗效分析
Analysis of Rationality and Therapeutic Efficacy of Antiemetics in Cancer Patients of Our Hospital
江彦 1宋洪涛1
作者信息
- 1. 南京军区福州总医院药学科，福州 350025
- 折叠
摘要
Abstract
OBJECTIVE:To provide reference for rational use of antiemetics in cancer patients. METHODS:Two thousand six hundred and sixteen pieces of medical orders of patients receiving antiemetics were collected from oncology department of our hospital via EMRS during Oct. 2015-Jun. 2016. RESULTS:Among 2 616 cases surveyed,1 301 cases conformed to inclusion and exclusion criteria,of which irrational use of drugs were found in 595 cases,760 times in total. Main manifestations were unsuitable drug selection(33.82%),irrational usage and dosage(25.26%),unsuitable drug combination(34.08%)and non-standard medication course(6.84%). The incidence of nausea in female was higher than male,with statistical sighificance(P=0.003),but gender had no significant effect on the incidence of nausea(P>0.05). Age had no significant effect on both nausea and vomiting(P>0.05). The control rate of nausea/vomiting in rational drug use group was higher than irrational drug use group. Average cost of antiemetic treatment of different emetic risk chemotherapy drugs in rational drug use group were all lower than irrational drug use group, indicating therapeutic efficacy could be guaranteed and economic burden was reduced in rational drug use group. CONCLUSIONS:The antiemetic plan should be selected rationally according to emetic risk degree of chemotherapy drugs. Patients receiving combined chemotherapy should select antiemetic plan according to highest emetic risk degree of chemotherapy drugs,and strictly master usage, dosage and duration. At the same time,treatment cost should be considered when selecting antiemetic plan to guarantee the safe, effective,economical and rational use of drugs.关键词
化疗/止吐药物/合理用药/疗效Key words
Chemotherapy/Antiemetics/Rational drug use/Therapeutic efficacy分类
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江彦,宋洪涛..我院肿瘤患者止吐药物使用合理性与疗效分析[J].中国药房,2017,28(5):602-606,5.
