中国药房2017，Vol.28Issue(8)：1066-1068,3.DOI:10.6039/j.issn.1001-0408.2017.08.16
加味硝黄贴辅助治疗胸腰椎骨折后麻痹性肠梗阻的临床观察
Clinical Observation of Modified Xiaohuang Paste in the Treatment of Paralytic Ileus after Thoracolumbar Fractures
摘要
Abstract
OBJECTIVE:To observe clinical efficacy and safety of Modified xiaohuang paste in the treatment of paralytic ileus after thoraeolumbar fractures.METHODS:One hundred and thirty-eight patients with paralytic ileus after thoracolumbar fractures were divided into control group (group A,43 cases),Xiaohuang paste group (group B,47 cases) and Modified xiaohuang paste group (group C,48 cases).Group A was given routine treatment as fasting,gastrointestinal decompression,fluid replacement,nutritional support;group B was additionally given Xiaohuang paste on the basis of group A;group C was additionally given Modified xiaohuang paste on the basis of group A.Group B and C were given relevant paste every 12 h until intestinal peristalsis was recovered and gas exhausted from anus,at the most for 5 days.The improvement time of clinical symptom improvement,VAS score and CRP level were compared among 3 groups as well as the occurrence of ADR.RESULTS:After treatment,the time of gastrointestinal decompression,bowel sound recovery and passage of gas by anus in group B and C were significantly shorter than group A,and group C was significantly shorter than group B,with statistical significance (P＜0.05).Before treatment,there was no statistical significance in VAS score and CRP level among 3 groups (P＞0.05).After treatment,VAS score of abdominal pain and distension,CRP level of 3 groups were decreased significantly compared to before treatment;those of group C were significantly lower than group A and B,and CRP level of group B was significantly lower than that of group A,with statistical significance (P＜0.05).There was no statistical significance in VAS score between group A and B (P＞0.05).No significant ADR was found in 3 groups.CONCLUSIONS:For paralytic ileus after thoracolumbar fracture,Modified xiaohuang paste can significantly shorten treatment duration,relieve abdominal distension and pain,inflammation with good safety.关键词
加味硝黄贴/胸腰椎骨折/麻痹性肠梗阻Key words
Modified xiaohuang paste/Thoracolumbar fracture/Paralytic ileus分类
医药卫生引用本文复制引用
罗亚丽,李辉映,王耀华,俞平,钱军..加味硝黄贴辅助治疗胸腰椎骨折后麻痹性肠梗阻的临床观察[J].中国药房,2017,28(8):1066-1068,3.基金项目
卫生部医药卫生科技发展研究中心课题(No.W2014ZT122) （No.W2014ZT122）
