中国医科大学学报2017，Vol.46Issue(2)：112-115,4.DOI:10.12007/j.issn.0258-4646.2017.02.004
血红蛋白和胆红素水平与广泛期小细胞肺癌预后的关系
Correlation of Hemoglobin and Bilirubin with Prognosis of Extensive Stage Small Cell Lung Cancer
摘要
Abstract
Objective To explore the factors that affect the prognosis of extensive small cell lung cancer by analyzing the association between lab-oratory indicators before treatment of extensive small cell lung cancer patients and the initial evaluation results with disease progression and overall survival. Methods This study retrospectively analyzed 96 cases of hospitalized patients in the medical oncology department of The First Hospital of China Medical University from March 2008 to September 2014. Kaplan-Meier method and Cox proportional hazards models were adopted to ana-lyze the relevant factors affecting the prognosis of extensive small cell lung cancer. P<0.05 was considered statistically significant. Results There was no obvious correlation between HB level before treatment with PFS of patients(P=0.179),but there was obvious significant correlation be-tween HB level and OS of patients(P=0.041). Our results showed that the TBIL level of patients before chemotherapy was significantly associated with the PFS(P=0.039)and OS(P=0.026)of patients. Conclusion HB and TBIL levels are the influencing factors that affect the prognosis and survival of patients with extensive small cell lung cancer.关键词
广泛期/小细胞肺癌/血红蛋白/胆红素/预后Key words
extensive stage/small cell lung cancer/hemoglobin/total bilirubin/prognosis分类
医药卫生引用本文复制引用
于溪,张彬彬,杨碧洁,张哲,马铭霞,邹佳运,赵明芳..血红蛋白和胆红素水平与广泛期小细胞肺癌预后的关系[J].中国医科大学学报,2017,46(2):112-115,4.基金项目
辽宁省科学技术计划(2014226033) （2014226033）
吴阶平医学基金会临床科研专项资助基金(320.6750.14287) （320.6750.14287）
