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217例2型糖尿病住院患者血糖波动的影响因素

王平 单忠艳 姜雅秋

中国医科大学学报2017,Vol.46Issue(3):244-247,4.
中国医科大学学报2017,Vol.46Issue(3):244-247,4.DOI:10.12007/j.issn.0258-4646.2017.03.013

217例2型糖尿病住院患者血糖波动的影响因素

Influencing Factors of Glycemic Variability in 217 Cases of Hospitalized Patients with Type 2 Diabetes

王平 1单忠艳 1姜雅秋1

作者信息

  • 1. 中国医科大学附属第一医院内分泌与代谢病科,内分泌研究所,辽宁省内分泌疾病重点实验室,沈阳 110001
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摘要

Abstract

Objective To explore the influencing factors of glycemic variability in 217 cases of hospitalized patients with type 2 diabetes. Meth-ods A total of 217 cases of hospitalized patients with type 2 diabetes,whom received continuous glucose monitoring from January 2013 to Janu-ary 2016,were enrolled for the study. The evaluation variables of glycemic variability included mean amplitude of glycemic excursion(MAGE) and standard deviation of blood glucose(SDBG). Results The difference of glycemic variability was compared by gender,age,diabetic duration, HbA1c,BMI. The values of MAGE and SDBG in females were higher than those in males(P<0.05). There was no significant difference between various age groups and various diabetic duration. The level of glycemic variability increased gradually with the extension of HbA 1c(P<0.05). The level of glycemic variability increased gradually with the extension of body mass index(BMI)(P<0.05). Logistic regression analysis showed that gender(OR=0.67,P=0.02),HbA1c(OR=0.8,P=0.02),diastolic blood pressure(OR=0.9,P=0.03),triglycerides(OR=4.6,P=0.007),cholesterol(OR=0.6,P=0.007). HDL-C(OR=0.09,P=0.006)were significant influencing factors of glycemic variability in hospital-ized patients with type 2 diabetes. Conclusion Gender,HbA1c,BMI,and blood fat are significant influencing factors of glycemic variability while age and duration are not related to the glycemic variability in hospitalized patients with type 2 diabetes.

关键词

血糖波动/动态血糖监测/2型糖尿病/平均血糖波动幅度/影响因素

Key words

glycemic variability/continuous glucose monitoring/type 2 diabetes/mean amplitude of glycemic excursion/influencing factor

分类

医药卫生

引用本文复制引用

王平,单忠艳,姜雅秋..217例2型糖尿病住院患者血糖波动的影响因素[J].中国医科大学学报,2017,46(3):244-247,4.

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