中国药业2017，Vol.26Issue(3)：11-14,4.DOI:10.3969/j.issn.1006-4931.2017.03.004
不同产地炮天雄的质量考察与比较
Quality Comparison of Pao Tianxiong from Different Producing Places
摘要
Abstract
Objective To study the quality of Pao Tianxiong from different producing places and to determine the difference between mono and di-ester alkaloids. Methods Kromasil 100-5-C18 column ( 250 mm × 4. 6 mm, 5 μm ) was used;the acetonitrile-tetrahydro-furan ( 25:15 ) was used as mobile phase A with 0. 1 mol/L ammonium acetate solution as mobile phase B, gradient. The flow rate was 1 mL/min;detection wavelength is 235 nm;column temperature is 30 ℃. Results Pao Tianxiong from Sichuan and Hubei had the highest amount of mono-ester alkaloid content;Pao Tianxiong from Sichuan and Hong Kong had the lowest amount of di-ester alkaloids which were toxic. Conclusion Pao Tianxiong produced in different places are affected by local indigenous herbs;more importantly, it is affect-ed by the processing experience and technology. Therefore, we need to make relevant standards for Pao Tianxiong as soon as possible.关键词
炮天雄/酯型生物碱/产地/高效液相色谱法Key words
Pao Tianxiong/ester alkaloids/place of origin/HPLC分类
医药卫生引用本文复制引用
覃军,邓广海,陈艳红,龚又明..不同产地炮天雄的质量考察与比较[J].中国药业,2017,26(3):11-14,4.基金项目
广东省科技计划项目[2016A040403104]. （）
