中国药业2017,Vol.26Issue(4):56-58,3.DOI:10.3969/j.issn.1006-4931.2017.04.016
甲氨蝶呤联合米非司酮治疗异位妊娠临床研究
Clinical Research on Methotrexate Combined with Mifepristone for Conservative Treatment of Ectopic Pregnancy
曹杰 1刘刚 1赵婷 1王佳1
作者信息
- 1. 重庆医科大学附属大学城医院妇产科,重庆 401331
- 折叠
摘要
Abstract
Objective To study the different clinical efficacy between methotrexate combined with mifepristone and the single use of methotrexate on the treatment of ectopic pregnancy. Methods 49 cases of patients diagnosed with ectopic pregnancy in the hospital between January 2015 and July 2016 were randomly divided into two groups,the single dose of methotrexate was applied in group A(n=28), and the single dose of methotrexate combined with oral mifepristone was applied in group B(n=21). The blood β-HCG of all patients was followed up until the clinical symptoms disappeared (< 7 U/L). Results 8 cases in group A failed in conservative treatment,the total effective rate was 71. 43%;1 case in group B failed in conservative treatment,the effective rate was 95. 24%. It took (37 ± 7. 4)d for group A to make the β-HCG decreased to normal and group B took (31 ± 4. 1)d. Conclusion Methotrexate combined with mifepristone for ectopic pregnancy can shorten the treatment time and improve the cure rate.关键词
异位妊娠/保守治疗/甲氨蝶呤/米非司酮Key words
ectopic pregnancy/conservative treatment/methotrexat/mifepristone分类
医药卫生引用本文复制引用
曹杰,刘刚,赵婷,王佳..甲氨蝶呤联合米非司酮治疗异位妊娠临床研究[J].中国药业,2017,26(4):56-58,3.