中国医院用药评价与分析2017,Vol.17Issue(2):218-221,4.DOI:10.14009/j.issn.1672-2124.2017.02.026
多省区白及高效液相色谱指纹图谱研究
Research on HPLC Fingerprint of Blerillae Rhizoma from Multiple Provinces
陈景 1阎婷 1贾景明2
作者信息
- 1. 沈阳药科大学中药学院,辽宁沈阳 110016
- 2. 锦州医科大学药学院,辽宁锦州 121001
- 折叠
摘要
Abstract
OBJECTIVE:To establish the HPLC fingerprint of Blerillae rhizoma from multiple provinces , so as to provide evidence for quality control of Blerillae rhizome .METHODS:HPLC method was adopted , the chromatographic separation was performed on Hypersi C18 (4.6 mm ×250 mm,5 μm) column, and the mobile phase consisting of acetonitrile-water in gradient elution .The flow rate was 1.0 ml/min, the detect wavelength was 270 nm and the column temperature was 35 ℃.RESULTS:There were 15 common peaks in the HPLC fingerprint of the 10 batches of Blerillae rhizoma from different producing areas .CONCLUSIONS: The HPLC fingerprint method was comprehensive and reliable for the quality control of Blerillae rhizome .关键词
白及/指纹图谱/高效液相色谱法/质量控制Key words
Blerillae rhizome/Fingerprint/HPLC/Quality control分类
医药卫生引用本文复制引用
陈景,阎婷,贾景明..多省区白及高效液相色谱指纹图谱研究[J].中国医院用药评价与分析,2017,17(2):218-221,4.