摘要
Abstract
OBJECTIVE:To investigate the regularities and characteristics of 131 cases of adverse drug reaction ( ADR) reports in Nanyang the First People ' s Hospital ( hereinafter referred to as "our hospital") , so as to provide reference for the rational drug use in clinic .METHODS:131 cases of ADR reported by our hospital to the National ADR Monitoring Center from 2015 were analyzed retrospectively in respects of the route of administration , related drug categories and ADR involved organs and ( or) systems and clinical manifestations , etc.RESULTS: Of the 131 ADR cases, intravenous infusion was the main route of administration that induced ADR (104 cases, 79.39%).The number of ADR cases induced by piperacillin/tazobactam , mezlocillin sodium and cefoperazone sodium and sulbactam sodium dominated the top 3 places, respectively 10 cases ( 12.66%) , 8 cases ( 10.13%) and 6 cases ( 7.59%) . Skin and its accessories damage (44 cases, 26.78%) were mainly performed, followed by systemic damage(19 cases, 12.42%) .CONCLUSIONS:The clinic should strengthen the ADR monitoring , closely monitor the severe ADR , and improve the rational drug use according to the occurrence regularities and characteristics of ADR , so as to reduce or avoid the occurrence of ADR .关键词
药品不良反应/分析/合理用药Key words
Adverse drug reactions/Analysis/Rational drug use分类
医药卫生
