中国真菌学杂志2017,Vol.12Issue(1):42-44,3.
1%卢立康唑乳膏治疗体股癣的疗效和安全性研究
Evaluation of efficacy and safety of 1% luliconazole cream in the treatment of tinea corporis and tinea cruris
摘要
Abstract
Objective To evaluate the efficacy and safety of 1% luliconazole cream in the treatment of tinea corporis and tinea cruris.Methods A single-center,single-blind,randomized,positive drug (1% terbinafine hydrochloride cream) controlled trial was conducted.Both 1% luliconazole cream and 1% terbinafine hydrochloride cream were applied once daily for 2 weeks to the rashes.Patients were evaluated at 0 (baseline),1,2 and 4 weeks.Results Thirty cases in the trial group and 28 cases in the control group were evaluated.The effective rate at 1 week was 43.33% in the trial group and 28.57% in the control group (P>0.05);96.67% versus 85.71% at 2 weeks and 96.67% versus 100.00% at 4 weeks respectively (P>0.05).Mycological cure rates at 1 week both were 50% in the trial group and control group;96.67% versus 85.71% at 2 weeks and 96.67% versus 100.00% at 4 weeks respectively (P>0.05).Treatment-related adverse events were not seen in this study.Conclusion This study suggests that 1% luliconazole cream was effective and safe in the treatment of tinea corporis and tinea cruris.关键词
卢立康唑/特比萘芬/体癣/股癣Key words
luliconazole/terbinafine/tinea corporis/tinea cruris分类
医药卫生引用本文复制引用
朱敏,粟慧琳,李莉,程本霖,朱均昊,章强强..1%卢立康唑乳膏治疗体股癣的疗效和安全性研究[J].中国真菌学杂志,2017,12(1):42-44,3.基金项目
中国中西医结合学会皮肤性病专业委员会临床研究基金(CAIM-LLKZ-007) (CAIM-LLKZ-007)